By Carl-Fredrik Mandenius
During this specialist instruction manual either the themes and members are chosen to be able to offer an authoritative view of attainable purposes for this new know-how. the result's an up to date survey of present demanding situations and possibilities within the layout and operation of bioreactors for high-value items within the biomedical and chemical industries.
Combining idea and perform, the authors clarify such modern applied sciences as single-use bioreactors, bioreactor simulators, and gentle sensor tracking, and speak about novel functions, comparable to stem mobilephone construction, strategy improvement, and multi-product reactors, utilizing case experiences from academia in addition to from undefined. a last part addresses the newest developments, together with tradition media layout and platforms biotechnology, that are anticipated to have an expanding impression on bioreactor design.
With its specialize in state-of-the-art applied sciences and discussions of destiny advancements, this instruction manual will stay a useful reference for a few years to come.
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Extra info for Bioreactors : design, operation and novel applications
108, 600–610. Hansen, F. (1965) Konstruktionssystematik, VEB Verlag, Berlin. Hubka, V. E. (1988) Theory of Technical Systems: A Total Concept Theory for Engineering Design, SpringerVerlag, Berlin. Pahl, G. and Beitz, W. (1996) Engineering Design, A Systematic Approach, SpringerVerlag, Berlin. T. D. (2007) Product Design and Development, 3rd edn, McGraw-Hill, New York. F. and Björkman, M. , Hoboken, NJ. F. and Björkman, M. (2010) Mechatronic design principles for biotechnology product development.
So far, most of these progressing activities are still in the academic research environment. In a few cases, they emerge as new products from Small and Mediumsized Enterprises (SMEs). Others are already in regular use at the process research and development units, especially at larger biotech companies. 4, here adapted to bioreactor design and operation with several of the topics and challenges addressed in this book. developed in-house by companies close to the applications and under knowledge protection.
6 Using Conceptual Design Methodology biosensors, biochips, diagnostic devices, and bioprocesses, at the same time as the work process is facilitated and speeded up. 8 recapitulates the cornerstones of the methodology: to precisely deﬁne and specify the needs and target metrics of the user or customer; to clearly deﬁne the expected transformation process (Trp) of the product or process and those systems that must interact with that process to carry it out eﬃciently; to consider all functional elements that must be present for this and to conﬁgure (or permute) these in a variety of more or less appealing alternatives; and, ﬁnally, to compare and assess these alternatives in order to screening out the ones that best cope with the original design and user targets.
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